Expression of Cytoskeleton & Cell Adhesion Molecules during Kidney Development

This table is part of the Kidney Development Database

For an explanation of the colunm headings, click here

Cytoskeleton

Gene
unind ub
duct tip
duct trunk
unind mm
blastema
cond-s
glom
neph
stroma
Remarks
References
Vimentin
n (mouse)
-
n (mouse)
?y (man)
n (mouse)
-
Y(mouse)
-
Y (mouse)
-
goes (mouse)
-
y (mouse)
-
n (mouse)
-
Y (mouse)
-
KO no effect
Holthofer 1984
Colucci-Guyon 1994
Cytokeratins
Y
Y
Y
n
n
Y
y & n cells
Y
n
-
Holthofer 1984
Garrod 1990
Cytokeratin 7
?
?
Y
n
n
n
n
n
n
human data
Moll 1991
EMAP-115
?
?Y
Y
n
n
Y
Y
Y
n
-
Fabre-Jonca 1998
Neurofilament
light chains
-
-
-
-
-
-
-
-
peritubular
+ neurons
Sainio 1994
Synaptopodium
-
-
-
n
n
n
podocytes
n
n
rat data
Mundel 1991
Utrophin
?
?
Y
?
?
?
?
Y
(y)
low mag pics
Schofield 1993
Desmin (2.7)
n
n
n
n
n
n
some cells
n
-
-
Bachmann 1983

 

Cell-cell adhesion molecules (see elsewhere for matrix adhesion)

Gene
unind ub
duct tip
duct trunk
unimd mm
blastema
cond-s
glom
neph
stroma
Remarks
Referencees
ACAM
Y
Y
lost
y
y
Y
?
Y-n
n
chick data
Duband 1988
Cx 26
-
-
-
-
-
-
-
proximal
-
-
Sainio 1992
Cx 32
-
-
-
-
-
-
-
proximal
-
-
Sainio 1992
Cx 43
-
-
-
y
y
Y
n
some
?
-
Sainio 1992
Desmocollin
Y
Y
Y
n
n
Y
Y
Y
n
-
Garrod 1990
Desmoglein
Y
Y
Y
n
n
Y
Y
Y
n
-
Garrod 1990
Desmoplakin
Y
Y
Y
n
n
Y
Y
Y
n
-
Garrod 1990
FAT
-
n
n
-
n
Y(S)
Y
Y
n
-
Dunne 1995
Gicerin
?
Y
Y
Y
Y
Y
Y goes
Y goes
?
chick data
Takaha 1995
L1
-
Y
Y
n
n
n
-
Henle
peritubular
see modifier table Sainio 1994
Debiec 1998
NCAM
?
?
?
y
y
Y
n
n
?
Ab no effect
KO no effect
see mutant table
Klein 1988
Vestweber 1985
Cremer 1994
PSA
Y
Y
lost
Y
Y
Y
n
n
lost
rat data |
Lackie 1990
Cadherin 6
-
-
-
n
n
Y some
-
Yproximal
-
see antibody
inhibition
Cho 1998
Cadherin 11
n
n
n
?
Y
-
-
-
-
see antibody
inhibition
Cho 1998
B-cadherin
-
-
-
n
n
Ysome
?
Ysome
-
chick data
Murphy-Erdosh 1994
E-cadherin
Y
Y
Y
n
n
Y
Y
Y
n
-
Klein 1988
K-cadherin
-
n
n
-
n
Y
Y early
Y lost later
n
rat data
Xiang 1994
P-cadherin
-
-
-
-
-
-
Y
-
-
-
Cho 1998
Z01
-
-
-
-
-
-
Y
-
-
-
Schnabel 1990
Gene
unind ub
duct tip
duct trunk
unind mm
blastema
cond-s
glom
neph
stroma
Remarks
References

Date of last revision: January 2006
Comments about the database are always welcome.
Email: Jamie.Davies@ed.ac.uk