Expression of Miscellaneous Proteins during Kidney Development

This table is part of the Kidney Development Database Kidney Development Database.

For an explanation of the colunm headings, click here.

Transporters

Gene
unind ub duct tip duct trunk unind mm blastema cond-s glom neph stroma Remarks
References
Anosmin1
-
n
Y
-
n
n
n
n
n
-
Hardelin 1999
Aquaporin 1
-
n
n
n
n
n
n
prox 12wk-
dist 15wk-
n
human data
Devuyst 1996
Aquaporin 2
?
Y
Y
n
n
n
n
n
n
human data
Devuyst 1996
Na/K ATPase
?
?
Y
n
n
n
?
Y
n
human data;
expression odd in PKD
Hennigar 1989
Band III
n
n
Y late
n
n
n
n
n
n
human data
Hennigar 1989
Carbonic anhydrase II
n
n
?
n
n
n
n
Y
n
human data
Hennigar 1989
CFTR
-
?y
Y 12wk-
-
-
-
-
prox, Henle
-
-
Devuyst 1996
K-Cl cotransporter
expressed somewhere in kidney (Northern data); functional evidence for expression in tubule cells
-
Gillen 1996
Na channel
n
n
Y
n
n
n
n
n
n
-
Watanabe 1999

Miscellaneous Enzymes

Gene
unind ub duct tip duct trunk unind mm blastema cond-s glom neph stroma Remarks
References
Acid phosphatase
Y
Y
Y
y
y
?
n
n
?
assay by activity
Catayee 1964
Glutathione S-transferase
-
-
-
?Y
Y
n
n
Y late
n
hamster data
Oberley 1991
11 beta-hydroxysteroid
dehydrogenase type II
somewhere in the kidney (Northern Blot and chemical assay data
sheep day E85->
Langlois 1995
Heparan sulfate
2-sulphotransferase
y
n
n
y
Y
goes
n
n
?
gene tag data
Bullock 1998
MMP-2
n?
Y(LeLongt)
n(Kanwar)
y(LeLongt)
n(Kanwar)
Y
Y
Y
?
?
?
-
Reponen 1992
LeLongt 1997
Kanwar 1999
MMP-9
?n
Y
y
?
?
Y
?
?
?
See modifier table
LeLongt 1997
MT-1-MMP
?Y
Y
y
n
n
-
-
-
-
-
Kanwar 1999
nos
-
-
-
-
-
-
Y late
-
neurons E20-
-
Huang 1993
Liu 1996
Galactosidase
?
(y)
(y)
n
n
n
?n
Y
n
-
Bard 1991
Protein phosphatase 1
all isoforms expressed ubiquitously in 15 day kidneys
 
rat data
Svennilson 1995
Protein phosphatase 2A
all isoforms expressed ubiquitously in 15 day kidneys
 
rat data
Svennilson 1995
Rab 17 GTPase
?
?
?
n
n
?Y
?
Y
n
-
Lutke 1993
Gene
unind ub duct tip duct trunk unind mm blastema cond-s glom neph stroma Remarks
References

Other Molecules.

Gene
unind ub duct tip duct trunk unind mm blastema cond-s glom neph stroma Remarks
References
Bradykinin








-
Penshcow 1992
Brush border antigen
n
n
n
n
n
n
n
distal
n
-
Miettinen 1986
CD15
n
n
n
n
n
n
n
proximal
-
-
Bard & Ross 1991
Davies 1994
Dentin sialoprotein
        n
      y
         y







Alvares 2006
FANCA
-
n
Y
n
n
n
n
n
n
-
Abu-Issa 1999
Histamine
-
-
-
-
-
-
-
conv tubus
-
-
Nissinen 1995
HMG-17
-
-
-
-
Y
Y
-
-
-
-
Lehtonen 2001
I-1
-
n
n
-
Y
n
n
n
n
inhibitor of protein phosphatases
Svennilson 1995
Kallikrein
-
-
-
-
-
-
-
Y E19-
-
-
Penschow 1992
Napsin
-
-
-
-
n
-
-
y
-
-
Mori 2001
Polycystin
-
y
y
-
n
y
y
y
n
-
Peters 1996
PrP
?
?
?
n
n
?Y
?
Y
n
-
Manson 1992
SGP-2
?
(y)
(y)
n
n
Y
n
distal
-
high in PKD
Harding 1991
TIMP-3
-
-
-
-
-
-
Y
Y
-
low res
Apte 1994
Uromucoid
n
n
n
n
n
n
n
distal
-
-
Hoyer 1974
Gene
unind ub duct tip duct trunk unind mm blastema
cond-s
glom
neph
stroma
Remarks
References

Date of last revision: November 2006  
Comments about the database are always welcome.
Email: Jamie.Davies@ed.ac.uk