Papers from this lab (most recent first): ORCID ID 0000-0001-6660-4032
Last update: July 2022.
Connolly CN, Alexander SPH, Davies JA, Spedding M (2022) Environmental pharmacology – dosing the environment. Brit J Pharmacol, in press.
Palakkan, A.A., Tarnick, J., Waterfall, M. et al. Production of kidney organoids arranged around single ureteric bud trees, and containing endogenous blood vessels, solely from embryonic stem cells. Sci Rep 12, 12573 (2022). https://doi.org/10.1038/s41598-022-16768-1
Tarnick J, Davies JA (2022) Introducing blood flow in kidney explants by engraftment onto the chick chorioallantoic membrane is not sufficient to induce arterial smooth muscle cell development. Biology Open (2022) 11 (7): bio059459.
https://doi.org/10.1242/bio.059459
Lawrence ML, Elhendawi M, Morlock M, Lui W, Lui S, Seidel L, Hohenstein PH, Sjogren AK, Davies JA (2022) Human iPSC-derived renal organoids, engineered to report oxidative stress, can predict drug-induced toxicity. iScience. 2022 Feb 7;25(3):103884. doi: 10.1016/j.isci.2022.103884
Davies JA (2022) Synthetic Morphogenesis: introducing IEEE journal readers to programming living mammalian cells to make structures. in Proceedings of the IEEE, doi: 10.1109/JPROC.2021.3137077
Davies JA & Brooks KE (2022) Gender neutrality in the teaching of partnered social dance. In Kitchener, M. ed. Handbook for Creating a Gender-Sensitive Curriculum: Teaching and Learning Strategies [Online]. Available from: https://www.brookes.ac.uk/ocsld/publications/.
Harding, S; Armstrong,; Faccenda, E; Southan, C; Alexander, SPH; Davenport, A; Pawson, A; Spedding, M; Davies, JA. and NC-IUPHAR (2022) The IUPHAR/BPS Guide to PHARMACOLOGY in 2022: curating pharmacology for COVID-19, malaria and antibacterials. Nucleic Acids Res. 2022 Jan 7;50(D1):D1282-D1294. doi: 10.1093/nar/gkab1010.
Alexander SP, Kelly E, Mathie A, Peters JA, Veale EL, Armstrong JF, Faccenda E, Harding SD, Pawson AJ, Southan C, Davies JA, Amarosi L, Anderson CMH, Beart PM, Broer S, Dawson PA, Hagenbuch B, Hammond JR, Inui KI, Kanai Y, Kemp S, Stewart G, Thwaites DT, Verri T. THE CONCISE GUIDE TO PHARMACOLOGY 2021/22: Transporters. Br J Pharmacol. 2021 Oct;178 Suppl 1:S412-S513. doi: 10.1111/bph.15543. PMID: 34529826.
Alexander SP, Cidlowski JA, Kelly E, Mathie A, Peters JA, Veale EL, Armstrong JF, Faccenda E, Harding SD, Pawson AJ, Southan C, Davies JA, Coons L, Fuller PJ, Korach KS, Young MJ. THE CONCISE GUIDE TO PHARMACOLOGY 2021/22: Nuclear hormone receptors. Br J Pharmacol. 2021 Oct;178 Suppl 1:S246-S263. doi: 10.1111/bph.15540. PMID: 34529827.
Alexander SP, Fabbro D, Kelly E, Mathie A, Peters JA, Veale EL, Armstrong JF, Faccenda E, Harding SD, Pawson AJ, Southan C, Davies JA, Boison D, Burns KE, Dessauer C, Gertsch J, Helsby NA, Izzo AA, Koesling D, Ostrom R, Pyne NJ, Pyne S, Russwurm M, Seifert R, Stasch JP, van der Stelt M, van der Vliet A, Watts V, Wong SS. THE CONCISE GUIDE TO PHARMACOLOGY 2021/22: Enzymes. Br J Pharmacol. 2021 Oct;178 Suppl 1:S313-S411. doi: 10.1111/bph.15542. PMID: 34529828.
Alexander SP, Fabbro D, Kelly E, Mathie A, Peters JA, Veale EL, Armstrong JF, Faccenda E, Harding SD, Pawson AJ, Southan C, Davies JA, Beuve A, Brouckaert P, Bryant C, Burnett JC, Farndale RW, Friebe A, Garthwaite J, Hobbs AJ, Jarvis GE, Kuhn M, MacEwan D, Monie TP, Papapetropoulos A, Potter LR, Schmidt HHHW, Szabo C, Waldman SA. THE CONCISE GUIDE TO PHARMACOLOGY 2021/22: Catalytic receptors. Br J Pharmacol. 2021 Oct;178 Suppl 1:S264-S312. doi: 10.1111/bph.15541. PMID: 34529829.
Alexander SP, Mathie A, Peters JA, Veale EL, Striessnig J, Kelly E, Armstrong JF, Faccenda E, Harding SD, Pawson AJ, Southan C, Davies JA, Aldrich RW, Attali B, Baggetta AM, Becirovic E, Biel M, Bill RM, Catterall WA, Conner AC, Davies P, Delling M, Virgilio FD, Falzoni S, Fenske S, George C, Goldstein SAN, Grissmer S, Ha K, Hammelmann V, Hanukoglu I, Jarvis M, Jensen AA, Kaczmarek LK, Kellenberger S, Kennedy C, King B, Kitchen P, Lynch JW, Perez-Reyes E, Plant LD, Rash L, Ren D, Salman MM, Sivilotti LG, Smart TG, Snutch TP, Tian J, Trimmer JS, Van den Eynde C, Vriens J, Wei AD, Winn BT, Wulff H, Xu H, Yue L, Zhang X, Zhu M. THE CONCISE GUIDE TO PHARMACOLOGY 2021/22: Ion channels. Br J Pharmacol. 2021 Oct;178 Suppl 1:S157-S245. doi: 10.1111/bph.15539. PMID: 34529831.
Alexander SP, Christopoulos A, Davenport AP, Kelly E, Mathie A, Peters JA, Veale EL, Armstrong JF, Faccenda E, Harding SD, Pawson AJ, Southan C, Davies JA, Abbracchio MP, Alexander W, Al-Hosaini K, Bäck M, Barnes NM, Bathgate R, Beaulieu JM, Bernstein KE, Bettler B, Birdsall NJM, Blaho V, Boulay F, Bousquet C, Bräuner-Osborne H, Burnstock G, Caló G, Castaño JP, Catt KJ, Ceruti S, Chazot P, Chiang N, Chini B, Chun J, Cianciulli A, Civelli O, Clapp LH, Couture R, Csaba Z, Dahlgren C, Dent G, Singh KD, Douglas SD, Dournaud P, Eguchi S, Escher E, Filardo EJ, Fong T, Fumagalli M, Gainetdinov RR, Gasparo M, Gerard C, Gershengorn M, Gobeil F, Goodfriend TL, Goudet C, Gregory KJ, Gundlach AL, Hamann J, Hanson J, Hauger RL, Hay DL, Heinemann A, Hollenberg MD, Holliday ND, Horiuchi M, Hoyer D, Hunyady L, Husain A, IJzerman AP, Inagami T, Jacobson KA, Jensen RT, Jockers R, Jonnalagadda D, Karnik S, Kaupmann K, Kemp J, Kennedy C, Kihara Y, Kitazawa T, Kozielewicz P, Kreienkamp HJ, Kukkonen JP, Langenhan T, Leach K, Lecca D, Lee JD, Leeman SE, Leprince J, Li XX, Williams TL, Lolait SJ, Lupp A, Macrae R, Maguire J, Mazella J, McArdle CA, Melmed S, Michel MC, Miller LJ, Mitolo V, Mouillac B, Müller CE, Murphy P, Nahon JL, Ngo T, Norel X, Nyimanu D, O'Carroll AM, Offermanns S, Panaro MA, Parmentier M, Pertwee RG, Pin JP, Prossnitz ER, Quinn M, Ramachandran R, Ray M, Reinscheid RK, Rondard P, Rovati GE, Ruzza C, Sanger GJ, Schöneberg T, Schulte G, Schulz S, Segaloff DL, Serhan CN, Stoddart LA, Sugimoto Y, Summers R, Tan VP, Thal D, Thomas WW, Timmermans PBMWM, Tirupula K, Tulipano G, Unal H, Unger T, Valant C, Vanderheyden P, Vaudry D, Vaudry H, Vilardaga JP, Walker CS, Wang JM, Ward DT, Wester HJ, Willars GB, Woodruff TM, Yao C, Ye RD. THE CONCISE GUIDE TO PHARMACOLOGY 2021/22: G protein-coupled receptors. Br J Pharmacol. 2021 Oct;178 Suppl 1:S27-S156. doi: 10.1111/bph.15538. PMID: 34529832.
Alexander SP, Kelly E, Mathie A, Peters JA, Veale EL, Armstrong JF, Faccenda E, Harding SD, Pawson AJ, Southan C, Buneman OP, Cidlowski JA, Christopoulos A, Davenport AP, Fabbro D, Spedding M, Striessnig J, Davies JA, Ahlers-Dannen KE, Alqinyah M, Arumugam TV, Bodle C, Dagner JB, Chakravarti B, Choudhuri SP, Druey KM, Fisher RA, Gerber KJ, Hepler JR, Hooks SB, Kantheti HS, Karaj B, Layeghi-Ghalehsoukhteh S, Lee JK, Luo Z, Martemyanov K, Mascarenhas LD, McNabb H, Montañez-Miranda C, Ogujiofor O, Phan H, Roman DL, Shaw V, Sjogren B, Sobey C, Spicer MM, Squires KE, Sutton L, Wendimu M, Wilkie T, Xie K, Zhang Q, Zolghadri Y. THE CONCISE GUIDE TO PHARMACOLOGY 2021/22: Introduction and Other Protein Targets. Br J Pharmacol. 2021 Oct;178 Suppl 1:S1-S26. doi: 10.1111/bph.15537. PMID: 34529830.
Glykofrydis F, Cachat E, Berzanskyte I, Dzierzak E and Davies JA (2021) Bioengineering Self-organizing Signalling Centres to Control Embryoid Body Pattern Elaboration. ACS Synthetic Biology .doi: 10.1021/acssynbio.1c00060
Ope access
May Sallam & Jamie Davies (2021) Connection of ES Cell-derived Collecting Ducts and Ureter-like Structures to Host Kidneys in Culture, Organogenesis, DOI: 10.1080/15476278.2021.1936785
Holland I & Davies JA (2020) Automation in the life science research laboratory. Frontiers in Bioengineering and Biotechnology 2020 Nov 13;8:571777. doi: 10.3389/fbioe.2020.571777
Open access
Davies JA (2021) SynPHARM and the Guide to Pharmacology database: a toolset for conferring drug control on engineered proteins. Proteins, http://dx.doi.org/10.1002/pro.3971
Opmn access
Sallam M, Palakkan A, Mills C, Tarnick J, Elhendawi M, Marson L, Davies JA (2020) Differentiation of contractile, ureter-like tissue from Embryonic Stem cell-derived ureteric bud and ex-fetu mesenchyme. JASN, ASN.2019101075. doi: 10.1681/ASN.2019101075
Davies JA, Glykofrydis F (2020) Engineering pattern formation and morphogenesis. Bioch Soc Trans 2020 Jun 30;48(3):1177-1185. doi: 10.1042/BST20200013
Open access
Alexander,S, Armstrong J, Davenport A, Davies J, Faccenda E, Harding S, Levi-Schaffer F, Pawson A; Southan C, Spedding M (2020) A rational roadmap for SARS-CoV-2/COVID-19 pharmacotherapeutic research and development. Brit J Pharmacol, http://dx.doi.org/10.1111/bph.15094
Alexander SPH, Kelly E, Mathie A, Peters JA, Veale EL, Armstrong JF, Faccenda E, Harding SD, Pawson AJ, Sharman JL, Southan C, Davies JA, CGTP Collaborators (2019) THE CONCISE GUIDE TO PHARMACOLOGY 2019/20: Transporters Br JPharmacol. 2019 Dec;176 Suppl 1:: S397-S493
Alexander SPH, Fabbro D, Kelly E, Mathie A, Peters JA, Veale EL,
Armstrong JF, Faccenda E, Harding SD, Pawson AJ, Sharman JL, Southan C Davies JA, CGTP Collaborators (2019) THE CONCISE GUIDE TO PHARMACOLOGY 2019/20: Enzymes Br J Pharmacol. 2019 Dec;176 Suppl 1:: S297-S396
Alexander SPH, Fabbro D, Kelly E, Mathie A, Peters JA, Veale EL, Armstrong JF, Faccenda E, Harding SD, Pawson AJ, Sharman JL, Southan C, Davies JA, CGTP Collaborators (2019) THE CONCISE GUIDE TO PHARMACOLOGY 2019/20: Catalytic receptors. Br J Pharmacol. 2019 Dec;176 Suppl 1:: S247-S296
Alexander SPH, Cidlowski JA, Kelly E, Mathie A, Peters JA, Veale EL, Armstrong JF, Faccenda E, Harding SD, Pawson AJ, Sharman JL, Southan S, Davies JA, CGTP Collaborators (2019) THE CONCISE GUIDE TO PHARMACOLOGY 2019/20: Nuclear hormone receptors. Br J Pharmacol.
2019 Dec;176 Suppl 1:: S229-S246
Alexander SPH, Mathie A, Peters JA, Veale EL, Striessnig J, Kelly E, Armstrong JF, Faccenda E, Harding SD, Pawson AJ, Sharman JL, Southan C, Davies JA, CGTP Collaborators (2019) THE CONCISE GUIDE TO PHARMACOLOGY 2019/20: Ion channels. Br J Pharmacol. 2019 Dec;176
Suppl 1:: S142-S228
Alexander SPH, Christopoulos A, Davenport AP, Kelly E, Mathie A, Peters JA, Veale EL, Armstrong JF, Faccenda E, Harding SD, Pawson AJ, Sharman JL, Southan S, Davies JA, CGTP Collaborators. (2019) THE CONCISE GUIDE TO PHARMACOLOGY 2019/20: G protein‐coupled receptors Br J
Pharmacol. 2019 Dec;176 Suppl 1:: S21-S141
Alexander SPH, Kelly E, Mathie A, Peters JA, Veale EL, Armstrong JF, Faccenda E, Harding SD, Pawson AJ, Sharman JL, Southan C, Buneman OP, Cidlowski JA, Christopoulos A, Davenport AP, Fabbro D, Spedding M,
Striessnig J, Davies JA; CGTP Collaborators.THE CONCISE GUIDE TO PHARMACOLOGY 2019/20: Introduction and Other Protein Targets. Br J Pharmacol. 2019 Dec;176 Suppl 1:S1-S20. doi: 10.1111/bph.14747.
Open access
Buneman P, Christie G, Davies JA, Dimitrellou R, Harding S, Pawson A, Sharman J, Wu Y (2019) Why data citation isn’t working, and what to do about it. Database,2020, 1–16 doi: 10.1093/databa/baaa022
Open access
Harding S.D., Faccenda E., Southan C., Pawson A.J., Maffia P. Alexander S.P.H.5 Davenport A.P., Fabbro D7,8., Levi-Schaffer F9., Spedding M10., Davies J.A. (2020) The IUPHAR Guide to Immunopharmacology:
Connecting Immunology and Pharmacology. Immunology. Feb 5. doi: 10.1111/imm.13175.
Open access
Davies JA, Murray P, Wilm B (2019) Regenerative Medicine Therapies. Curr Physiol. https://doi.org/10.1016/j.cophys.2019.12.008
Open access
Fischbach P, Gonschorek P, Baaske J, Davies JA, Weber W, Zurbriggen MD (2020) Optogenetic downregulation of protein expression levels to control programmed cell death in mammalian cells with a dual blue-light switch. Meth Mol Biol Methods Mol Biol. 2020;2173:159-170.
doi: 10.1007/978-1-0716-0755-8_11
Open access
Jane F. Armstrong JF, Faccenda E, Harding SD, A J Pawson AJ, Southan C, Sharman JL, Campo B, Alexander SPH, Davenport AP, Spedding M, Cavanagh DR, Davies JA. The IUPHAR/BPS Guide to PHARMACOLOGY in 2020: extending immunopharmacology content and introducing the
IUPHAR/MMV Guide to MALARIA PHARMACOLOGY. Nucl Acids Res 2019 Nov 6. pii: gkz951. doi: 10.1093/nar/gkz951.
Open access
Davies JA, Ireland S, Harding S, Sharman J, Southan C, Dominguez-Monedero A. (2019) Inverse Pharmacology: approaches and tools for introducing druggability into engineered proteins. Biotechnology Advances 2019 Sep 5:107439. doi: 10.1016/j.biotechadv.2019.107439.
Open Access
Davies JA, Armstrong J (2019) The Buzz and the Byte. Pharmacology International 92: Guide2:1-3.
Waites W, Davies JA (2019) Emergence of structure in mouse embryos: structural entropy morphometry applied to digital models of embryonic anatomy. J Anat. Jul 5. doi: 10.1111/joa.13031.
Open Access.
Chang C-H, Davies JA (2019) In developing mouse kidneys, orientation of loop of Henle growth is adaptive and guided by long-range cues from medullary collecting ducts. J Anat. 235(2):262-270. doi: 10.1111/joa.13012.
Open Access.
Munro DAD, Wineberg Y, Vink CS, Tarnick J, Li Z, Dzierzak E, Kalisky T, Hohenstein P, Davies JA (2019) Macrophages restrict the nephrogenic field and promote endothelial connections during kidney development.
Elife 2019;8:e43271. DOI: https://doi.org/10.7554/eLife.43271
Open Access
Davies JA (2019) Real-world synthetic biology: is it founded on an engineering approach, and should it be?. Life 9, 6; doi:10.3390/life9010006.
Open Access.
Harding SD, Faccenda E, Southan C, Maffia P, Davies JA (2018) A new guide to immunopharmacology. Nat Rev Immunol doi 10.1038/s41577-018-0079-2.
Access at journal site.
Baaske J, Gonschorek P, Engesser R, Dominguez-Monedero A, Raute K, Fischbach P, Müller K, Schamel WWA, Minguet S, Davies JA, Timmer J, Weber W, Zurbriggen MD (2018)
"Dual-controlled optogenetic system for the rapid down-regulation of protein levels in mammalian cells" Sci Rep 8(1):15024. doi: 10.1038/s41598-018-32929-7.
Full paper.
Dominguez-Monedero A, Davies JA (2018) Tamoxifen- and mifepristone-inducible versions of CRISPR effectors, Cas9 and Cpf1. ACS Synthetic Biology, 7(9):2160-2169. doi: 10.1021/acssynbio.8b00145.
Access at journal site.
Southan C, Sharman JL, Faccenda E, Pawson AJ, Harding SD, Davies JA (2018) Challenges of connecting chemistry to pharmacology: perspectives from curating the IUPHAR/BPS Guide to PHARMACOLOGY. ACS Omega 3(7):8408-8420. doi: 10.1021/acsomega.8b00884.
Access at journal site.
Waites W, Cavaliere M, Cachat E, Danos V, Davies JA (2018). An information-theoretic measure for patterning in epithelial tissues. IEEE Access 6: 40302-40312 DOI: 10.1109/ACCESS.2018.2853624
Access at journal site.
Ireland SM, Southan C, Dominguez-Monedero A, Harding SD, Sharman JL, Davies JA (2018) SynPharm, a Guide to PHARMACOLOGY database tool for designing drug control into engineered proteins. ACS Omega, 3(7):7993-8002. doi: 10.1021/acsomega.8b00659
Access at journal site.
Munro DAD, Davies JA (2018) Perspective: Vascularizing the kidney in the embryo and organoid: questioning assumptions about renal vasculogenesis.
J Am Soc Nephrol. 29(6):1593-1595. doi: 10.1681/ASN.2018020179.
Pubmed.
Lawrence ML, Smith J, Davies JA (2018) Functional Transport of Organic Anions and Cations in the Murine Mesonephros. Am. J. Physiol. Renal Physiol., Mar 21 doi: 10.1152/ajprenal.00021.2018.
PubMed.
Elhendawi M, Davies JA (2018) Sebinger Culture: a System Optimized for Morphological Maturation and Imaging of Cultured Mouse Metanephric
Primordia. Bio-protocol 8(4): e2730. DOI: 10.21769/BioProtoc.2730.
Open access copy
Sharman J, Faccenda E, SHarding S, Pawson A, Southan C, Davies JA and NC-IUPHAR. Accessing expert-curated pharmacological data in the
IUPHAR/BPS Guide to PHARMACOLOGY. Current Protocols in Bioinformatics. https://doi.org/10.1002/cpbi.46.
Journal Site
Davies JA (2018) Adaptive self-organization in the embryo: its importance to adult anatomy and to tissue engineering. J Anat 232: 524-533.
Pubmed.
Davies JA (2018) – Self-Organizing Anatomy. Commentary for Gray’s Anatomy.
Harding SD, Sharman JL, Faccenda E, Southan C, Pawson AJ, Ireland S, Gray AJG, Bruce L, Alexander SPH, Anderton S, Bryant C, Davenport AP, Doerig C, Fabbro D, Levi-Schaffer F, Spedding M, Davies JA and NC-IUPHAR (2017).
The IUPHAR/BPS Guide to PHARMACOLOGY in 2018: Updates and expansion to encompass the new Guide to IMMUNOPHARMACOLOGY. Nucl. Acids Res. gkx1121, https://doi.org/10.1093/nar/gkx1121.
Pubmed.
Mills CG, Lawrence ML, Mullins JM, Davies JA (2017) Asymmetric BMP4 signalling improves the realism of kidney organoids.. Sci Rep. 2017 Nov 1;7(1):14824. doi: 10.1038/s41598-017-14809-8.
Pubmed Central
Davies JA (2017) Organizing organoids: stem cells branch out. Cell Stem
Cell, 21:705-706. doi: 10.1016/j.stem.2017.11.011.
Pubmed.
Munro DAD, Hohenstein P, Coate TM, Davies JA (2017) Refuting the hypothesis that semaphorin-3f/neuropilin-2 exclude blood vessels from the cap mesenchyme in the developing kidney. Developmental Dynamics. 246(12):1047-1056. doi: 10.1002/dvdy.24592
Pubmed.
Alexander SPH, Kelly E, Marrion NV, Peters JA, Faccenda E, Harding SD, Pawson AJ, Sharman JL, Southan C, Buneman OP, Clidowslki JA,Christopoulos A, Davenport AP, Fabbro D, Spedding M, Streissnig J, Davies JA and CGTP Collaborators (2017) The Concise Guide to PHARMACOLOGY 2017/18: Overview. British Journal of Pharmacology (2017) 174, S1–S16
Pubmed.
Alexander SPH, Christopoulos A, Kelly E, Marrion NV, Peters JA, Faccenda E, Harding SD, Pawson AJ, Sharman JL, Southan C, Davies JA and CGTP Collaborators (2017) The Concise Guide to PHARMACOLOGY 2017/18: G protein-coupled receptors.
British Journal of Pharmacology (2017) 174, S17– S129.
Pubmed.
Alexander SPH, Peters JA, Kelly E, Marrion NV, Faccenda E, Harding SD, Pawson AJ, Sharman JL, Southan C, Davies JA and CGTP Collaborators (2017) The Concise Guide to PHARMACOLOGY 2017/18: Ligand-gated ion channels.
British Journal of Pharmacology (2017) 174, S130–S159
Pubmed.
Alexander SPH, Striessnig J, Kelly E, Marrion NV, Peters JA, Faccenda E, Harding SD, Pawson AJ, Sharman JL, Southan C, Davies JA and CGTP Collaborators (2017) The Concise Guide to PHARMACOLOGY 2017/18: Voltage-gated ion channels.
British Journal of Pharmacology (2017) 174, S160–S194
Pubmed.
Alexander SPH, Kelly E, Marrion NV, Peters JA, Faccenda E, Harding SD, Pawson AJ, Sharman JL, Southan C, Davies JA and CGTP Collaborators (2017) The Concise Guide to PHARMACOLOGY 2017/18: Other ion channels.
British Journal of Pharmacology (2017) 174, S195–S207
Pubmed.
Alexander SPH, Cidlowski JA, Kelly E, Marrion NV, Peters JA, Faccenda E, Harding SD, Pawson AJ, Sharman JL, Southan C, Davies JA and CGTP Collaborators (2017) The Concise Guide to PHARMACOLOGY 2017/18: Nuclear hormone receptors.
British Journal of Pharmacology (2017) 174, S208–S224
Pubmed.
Alexander SPH, Fabbro D, Kelly E, Marrion NV, Peters JA, Faccenda E, Harding SD, Pawson AJ, Sharman JL, Southan C, Davies JA and CGTP Collaborators (2017) The Concise Guide to PHARMACOLOGY 2017/18: Catalytic receptors.
British Journal of Pharmacology (2017) 174, S225–S271
Pubmed.
Alexander SPH, Fabbro D, Kelly E, Marrion NV, Peters JA, Faccenda E, Harding SD, Pawson AJ, Sharman JL, Southan C, Davies JA and CGTP Collaborators (2017) The Concise Guide to PHARMACOLOGY 2017/18: Enzymes.
British Journal of Pharmacology (2017) 174, S272–S359
Pubmed
Alexander SPH, Kelly E, Marrion NV, Peters JA, Faccenda E, Harding SD, Pawson AJ, Sharman JL, Southan C, Davies JA and CGTP Collaborators (2017) The Concise Guide to PHARMACOLOGY 2017/18: Transporters.
British Journal of Pharmacology (2017) 174, S360–S446
Pubmed.
Cachat E, Liu W, Davies JA (2017) Synthetic self-patterning and morphogenesis in mammalian cells: a proof-of-concept step towards the goal of synthetic tissue
development. IET Engineering Biology doi: 10.1049/enb.2017.0013
Open access at journal site.
Martin KC, Yuan X, Stimac G, Bannerman K, Anderson J, Roy C, Yin H, Davies JA. (2017) Symmetry breaking in branching epithelia:
cells on micro patterns under flow challenge the hypothesis of positive feedback by a secreted autocrine inhibitor of motility.
J. Anat., 230: 766-774 doi: 10.1111/joa.12599.
Pubmed Central.
Tabriz, A.G., Mills, C.G., Mullins, J.J., Davies, J.A. Shu, W. (2017) Rapid fabrication of cell-laden alginate hydrogel 3D
structures by micro dip-coating. Frontiers in Bioengineering and Biotechnology. 5:13. doi: 10.3389/fbioe.2017.00013.
Pubmed Central.
Davies J. A. (2017) Using synthetic biology to explore principles of development. Review for Development. 144: 1146-1158; doi:10.1242/dev.144196
Pubmed.
Davies JA (2017) Pax2: a 'Keep to the path' sign on Waddington's epigenetic landscape. Developmental Cell 41: 331-332.
Pubmed.
Munro DAD, Hohenstein P, Davies JA (2017) Cycles of vascular plexus formation within the nephrogenic zone of the developing mouse kidney. Sci Rep
7(1):3273. doi: 10.1038/s41598-017-03808-4.
Pubmed.
Davies JA (2017) Binding Assets in Drug Design. Eureka May issue.
Eureka Site.
Davies JA (2017) The inter-dependence of basic and applied biomedical sciences: lessons from kidney development and tissue-engineering. Porto
Biomed J. 2: 136-139
Journal Site.
Davies JA (2016) Machines for living in: connections and contrasts between designed architecture and the development of living forms. Architectural Research Quarterly 20.1: 45-50
Davies JA (2016) Anatomical complexity is acquired at an exponential rate during mouse embryonic development. Matters doi 10.19185/matters.201604000005
Journal Site.
Davies JA & Cachat E (2016) Synthetic biology meets tissue engineering. Bioch Soc Trans. 44: 696-701
Pubmed.
Cachat E, Liu W, Martin KC, Yuan X, Yin H, Hohenstein P, Davies JA (2016) 2- and 3-dimensional synthetic de novo large-scale patterning by mammalian cells through phase separation. Scientific Reports 6:20664. doi: 10.1038/srep20664.
Pubmed.
Alexander SP, Davenport AP, Kelly E, Marrion N, Peters JA, Benson HE, Faccenda E, Pawson AJ, Sharman JL, Southan C, Davies JA, Collaborators C. (2015) The Concise Guide to PHARMACOLOGY 2015/16: G protein-coupled receptors. Br J Pharmacol. 172(24):5744-5869. doi: 10.1111/bph.13348.
Pubmed.
Alexander SP, Peters JA, Kelly E, Marrion N, Benson HE, Faccenda E, Pawson AJ, Sharman JL, Southan C, Davies JA; CGTP Collaborators. (2015) The Concise Guide to PHARMACOLOGY 2015/16: Ligand-gated ion channels. Br J Pharmacol. 2015 Dec;172(24):5870-5903. doi: 10.1111/bph.13350.
Pubmed.
Alexander SP, Catterall WA, Kelly E, Marrion N, Peters JA, Benson HE, Faccenda E, Pawson AJ, Sharman JL, Southan C, Davies JA; CGTP Collaborators. (2015) The Concise Guide to PHARMACOLOGY 2015/16: Voltage-gated ion channels. Br J Pharmacol. 172(24):5904-5941. doi: 10.1111/bph.13349.
Pubmed.
Alexander SP, Kelly E, Marrion N, Peters JA, Benson HE, Faccenda E, Pawson AJ, Sharman JL, Southan C, Davies JA, Collaborators C. (2015) The Concise Guide to PHARMACOLOGY 2015/16: Other ion channels. Br J Pharmacol. 172(24):5942-5955. doi: 10.1111/bph.13351.
Pubmed.
Alexander SP, Cidlowski JA, Kelly E, Marrion N, Peters JA, Benson HE, Faccenda E, Pawson AJ, Sharman JL, Southan C, Davies JA; CGTP Collaborators. (2015) The Concise Guide to PHARMACOLOGY 2015/16: Nuclear hormone receptors. Br J Pharmacol. 172(24):5956-5978. doi: 10.1111/bph.13352.
Pubmed.
Alexander SP, Fabbro D, Kelly E, Marrion N, Peters JA, Benson HE, Faccenda E, Pawson AJ, Sharman JL, Southan C, Davies JA; CGTP Collaborators. (2015) The Concise Guide to PHARMACOLOGY 2015/16: Catalytic receptors. Br J Pharmacol. 172(24):5979-6023. doi: 10.1111/bph.13353.
Pubmed.
Alexander SP, Fabbro D, Kelly E, Marrion N, Peters JA, Benson HE, Faccenda E, Pawson AJ, Sharman JL, Southan C, Davies JA, Collaborators C. (2015) The Concise Guide to PHARMACOLOGY 2015/16: Enzymes. Br J Pharmacol. 172(24):6024-6109. doi: 10.1111/bph.13354.
Pubmed.
Alexander SP, Kelly E, Marrion N, Peters JA, Benson HE, Faccenda E, Pawson AJ, Sharman JL, Southan C, Davies JA; CGTP Collaborators. (2015) The Concise Guide to PHARMACOLOGY 2015/16: Transporters. Br J Pharmacol. 172(24):6110-6202. doi: 10.1111/bph.13355.
Pubmed.
Alexander SP, Kelly E, Marrion N, Peters JA, Benson HE, Faccenda E, Pawson AJ, Sharman JL, Southan C, Buneman OP, Catterall WA, Cidlowski JA, Davenport AP, Fabbro D, Fan G, McGrath JC, Spedding M, Davies JA; CGTP Collaborators. (2015) The Concise Guide to PHARMACOLOGY 2015/16: Overview. Br J Pharmacol. 172(24):5729-5743. doi: 10.1111/bph.13347.
Pubmed.
Davies JA (2015) The IUPHAR/BPS Guide to Pharmacology: construction phase completed. Pharmacology International 85: 1-2
Open Access via IUPHAR site.
Davies JA (2015) Synthetic biology: rational pathway design for regenerative medicine. Gerontology DOI 10.1159/000440721
Pubmed.
Davies JA (2015) Biological techniques: Kidney tissue grown from induced stem cells. Nature, 526: 512-3.
Pubmed.
Southan C, Sharman J, Benson H, Facenda E, Pawson A, Alexander SPH, Buneman OP, Davenport A, McGrath JC, Peters J, Spedding M, Catterall W, Fabbro D, Davies J (2016) The IUPHAR/BPS Guide to Pharmacology in 2016:
Towards curated quantitiative interactions between 1300 protein targets and 6000 ligands. Nulc. Acids Res. 2015 Oct 12. pii: gkv1037.
Pubmed.
Davies JA (2015) Self-organized kidney rudiments: prospects for better in vitro nephrotoxicity assays. Biomarker Insights 2015:10(S1) 117-123
Pubmed.
Berry RL, Ozdermir D, Aronow B, Dudmakova T, Thornburn A, Lindström N, Perry P, Baldock R, Armit C, Jeanpiere C, Shan J, Vainio S, Bailey J, Brownstein D, Davies JA, Hastie N, Hohenstein P. (2015) Deducing the stage of origin of Wilms' tumours from a developmental series of Wt1-mutant mice
Disease Models and Mechanisms, 8(8):903-17. doi: 10.1242/dmm.018523.
Pubmed.
Cachat E, Martin KC, and Davies JA (2015) Synthetic Biology Approaches for Regenerative Medicine. In Meyers RA (Ed.) Synthetic Biology. Wiley-Blackwell ISBN: 978-3-527-33482-7
Georgas KM, Armstrong J, Keast JR, Larkins CE, McHugh KM, Southard-Smith M, Cohn M, Batourina E, Baldock RA, Brennan J, Buehler DP, Dan H, Davies JA, Harding SD, Richardson E, Schneider K, Wiese CB, Little MH, Vezina CM, Mendelsohn C. (2015) An illustrated anatomical ontology of the developing mouse lower urogenital tract.
Development 142(10):1893-908. doi: 10.1242/dev.117903.
Pubmed.
Combes AN, Davies JA, Little MH (2015) Cell-cell interactions driving kidney morphogenesis.
Curr Top Dev Biol 112: 467-508.
PubMed
Lawrence M, Davies JA (2015) Transport of organic anions and cations in engineered kidneys and in murine embryonic kidney development.
Scientific Reports 5:9092.
PubMed
Lindstrom N, Lawrence M, Burn S, Johansson J, Bakker E, Ridgway R, Chang C-H, Karolak M, Oxburgh L, Headon D, Sansom O, Smits R, Davies J,
Hohenstein P (2015) Integrated beta-catenin, BMP, PTEN, and Notch signalling patterns the nephron.
Elife. 2015 Feb 3;4:e04000. doi: 10.7554/eLife.04000.
PubMed
Cachat E, Liu W, Hohenstein P, Davies JA (2014) A library of mammalian effector modules for synthetic morphology.
Biol Eng. 19;8(1):26. doi: 10.1186/1754-1611-8-26.
PubMed
Lindstrom NO, Chang C-H, Valerius MT, Hohenstein P, Davies JA (2015) Node retraction during patterning
of the urinary collecting duct system.
J. Anat. 226:13-21.
PubMed
Davies JA, Hohenstein P, Chang C-H, Berry R (2014) A self-avoidance mechanism in patterning of the
urinary collecting duct tree.
BMC Dev Biology 2014 Sep 10;14(1):35.
PubMed
Davies JA (2014) A closed loop: The DNA helix gave 20th-century biology its symbol. But the more we learn, the more life circles back to an older image. Aeon magazine.
Magazine Page
Davies JA, Chang C-H, Lawrence ML, Mills CG, Mullins JJ (2014)
Engineered kidneys: principles,
progress and prospects. Adv. Regen Biol. 1: 24990 .
Journal Open Access
Davies JA (2014)
The urinary system. Chapter for supplement to Kaufman's
Atlas of Mouse Development. Elsevier/ Academic Press, in press.
Davies JA (2014)
Engineered renal tissue as a potential platform for pharmacokinetic and nephrotoxicity testing. Drug Discovery Today 19: 725-729.
PubMed
Davies JA (2014)
Epithelial branching: mechanisms of patterning and self- organization. Chapter for
Moody S (Ed.)
Principle of Developmental Genetics (2nd Edition).
Davies JA (2013)
Disinherited daughters travel by tube. Dev Cell 27(3):245-6.
PubMed
Davies JA (2013) Engineered renal tissue as a potential platform for
pharmacokinetic and nephrotoxicity testing.
Drug Discovery Today 19: 725-729.
PubMed
Davies JA (2013) Poor Edward, a scientific afterword/analysis for Sara Maitland's story
Seeing Double, in her book
Moss Witch. Comma Press.
Lindström NO, Hohenstein P, Davies JA. (2013) Nephrons require Rho-kinase
for proximal-distal polarity development.
Scientific Reports 3:2692.
doi: 10.1038/srep02692.
PubMed
Davies JA & Chang C-H (2013) Engineering kidneys from simple cell
suspensions: an exercise in self-organization.
Paed Neprhol 29(4):519-24.
PubMed
Davies JA (2013) Kidney Development.
Encyc Life Sci article A23672
Cachat E, Martin KC, Davies JA (2013) Synthetic Biology Approaches for
Regenerative Medicine. Article for
Encyc Molec Biol Molec Med
Tai G, Davies JA (2013) FAK/Src signalling is important to renal collecting duct
morphogenesis: discovery using a hierarchical screening technique.
Biology
Open 0, 1-8. doi 10.1242/bio.20133780
PubMed
Chang C-H, Davies JA. (2012) An improved method of renal tissue engineering,
by combining renal dissociation and re-aggregation with a low-volume culture
technique, results in development of engineered kidneys complete with loops of
Henle.
Nephron: Experimental Nephrology. 121:e79-e85
(DOI: 10.1159/000345514)
PubMed
Xinaris C, Benedetti V, Rizzo P, Abbate M, Corna D, Azzolini N, Unbekandt M,
Davies JA, Morigi M, Benigni A, and G. Remuzzi G (2012) Engineering of
nephrons that are vascularized and functional in vivo, from simple suspensions of
embryonic precursor cells.
JASN 23:1857-68
PubMed
Partridge R, Conlisk N, Davies JA (2012) In-lab 3-dimensional printing: an
inexpensive tool for experimentation and visualization for the field of
organogenesis.
Organogenesis 8(1):22-7.
PubMed
Davies JA (Ed.) (2012)
Tissue Regeneration InTech ISBN: 978-953-307-876-2
Woolf AS, Davies JA (2012) Cell Biology of Ureter Development.
JASN 24:19-25.
PubMed
Cachat E & Davies JA (2012) Application of synthetic biology to regenerative
medicine.
J Bioeng Biomed Sci doi 2155-9538.S2-003
Kuzma-Kuzniarska M, Kenny S, Edgar D, Wilm B, Davies J A., Murray P
(2012) Integration potential of mouse and human bone marrow-derived
mesenchymal stem cells.
Differentiation 83:128-37
PubMed
Chi L, Skovorodkin I, Anthony S, Davies J and Seppo Vainio S (2012) A secreted BMP antagonist, Cer1, fine tunes the spatial organization of the ureteric bud tree during mouse kidney development..
PloS ONE 2011;6(11):e27676.
PubMed
Davies JA (2012)
Replacing animal
models: a practical guide to creating and using culture-based biomimetic
alternatives (Ed. Davies JA) Wiley-Blackwell.
Amazon.
Davies JA (2012) Potential advantages of using biomimetic alternatives. Chapter for
Replacing animal
models: a practical guide to creating and using culture-based biomimetic
alternatives (Ed. Davies JA) Wiley-Blackwell
Tai G, Davies JA (2012) Immortalized cell lines as high-throughput alternative
to animal experiments in screens for pathways that control renal development. Chapter for
Replacing animal
models: a practical guide to creating and using culture-based biomimetic
alternatives (Ed. Davies JA) Wiley-Blackwell
Davies JA (2012) Culture of Foetal Kidney Chapter for
Replacing animal
models: a practical guide to creating and using culture-based biomimetic
alternatives (Ed. Davies JA) Wiley-Blackwell
Davies JA, Little M, Aronow B, Armstrong J, Brennan J, Lloyd-MacGilp S,
Armit C, Harding S, Piu X, Rochun Y, Haggarty B, Houghton D, Davidson D,
Baldock R (2012) Access and use of the GUDMAP database of mouse urogenital development.
Methods Molec Biol 2012;886:185-201
PubMed
Davies JA, Unbekandt (2012) RNA interference in renal organ culture.
Methods Molec Biol 886:295-303
PubMed
Tai G, Hohenstein P, Davies JA (2012) Making immortalized cell lines
from embryonic mouse kidney, to use as an alternative to in vivo experiments
in renal research.
Methods Molec Biol 886:165-71
PubMed
Davies JA, Unbekandt M, Ineson J, Lusis M, Little M (2012) Dissociation
of embryonic kidney followed by re-aggregation as a method for chimaeric
analysis.
Methods Molec Biol 2012;886:135-46
PubMed
Davies JA (2011) Self-organization as a tool in mammalian tissue engineering.
Chapter for Regenerative Medicine (Ed Winslet-Gendebien, S). 261-274.
Intech. ISBN 978-953-307-838-0.
http://www.intechopen.com/articles/show/title/self-organization-as-a-tool-in-mammalian-tissue-engineering
Essafi A, Webb A, Berry RL, Slight J, Burn SF, Spraggon L, Velecala V,
Martinez-Estrada OM, Wiltshire JH, Roberts SGE, Davies JA, Hastie ND,
Hohenstein P (2011) A Wt1-controlled chromatin switching mechanism
underpins tissue-specific Wnt4 activation and repression.
Dev Cell. 21:559-74
PubMed
Harding, S.D., Armit, C., Armstrong, J., Brennan, J., Cheng Y, Haggarty B,
Houghton, D., Lloyd-MacGilp, S., Pi, X., Roochun Y, Sharghi, M., Tindal C,
McMahon A, Goodison B, Little MH, Georgas K, Aronow B, Baldock RA,
Davies JA, Davidson, D. (2011) The GUDMAP Database - An Online
Resource for Genitourinary Research.
Development 138: 2845-2853.
PubMed
Burn SF, Webb A, Berry RL, Davies JA, Hastie ND, Hohenstein P (2011)
Calcium/ NFAT signalling promotes early nephrogenesis.
Dev Biol 352: 288-298
PubMed
Ganeva V, Unbekandt M, Davies JA (2011) An improved kidney dissociation
and re-aggregation culture system results in nephrons arranged
organotypically around a single collecting duct system.
Organogenesis 2011
Apr 1;7(2):83-7
PubMed
Berry R, Harewood L, Pei L, Fisher M, Brownstein D, Ross A, Moss J,
Hastie ND, Hohenstein P, Davies J, Evans RM, FitzPatrick DR (2011) Esrrg
functions in early branch generation of the ureteric bud and is essential for
normal development of the renal papilla.
Human Molecular Genetics
20: 917-26.
PubMed
Lee W-C, Hough M T, Liu W, Ekiert R, Lindstrom N O, Hohenstein P,
Davies JA (2010) Dact2 is expressed in renal collecting ducts and controls
morphogenetic behaviour of renal epithelial cells.
Am J Physiol 299(4): F740-751.
Siegel N, Rosner M, Unbekandt M, Fuchs C, Slabina N, Dolznig H,
Davies JA, Lubec G, Hengstschl‰ger M (2010) Contribution of human
amniotic fluid stem cells to renal tissue formation depends on mTOR.
Hum Molec Genet 19: 3320-31.
PubMed
Sebinger DDR, Unbekandt U, Ganeva V, Ofenbauer A, Werner C & Davies
JA (2010) A novel, low-volume method for organ culture of embryonic
kidneys that allows development of cortico-medullary anatomical
organization.
PLoS One 5(5): e10550. doi:10.1371/journal.pone.0010550
PubMed
Davies JA (2010) The embryonic kidney: isolation, organ culture,
immunostaining and RNA interference.
Meth Molec Biol 633:57-69.
PubMed
Unbekandt M, Davies JA (2010) Dissociation of embryonic kidneys followed
by reaggregation allows the formation of renal tissues.
Kidney International
77: 406-416
PubMed
Davies JA (2009)
Regulation, necessity, and the misinterpretation of knockouts.
BioEssays 31:826-30
PubMed
Davies JA (2009)
Synthetic morphology: modules for engineering biological form. In Columbus F
(Ed.),
Synthetic Biology: Parts and Systems,
Design Theory and Applications in press.
Davies JA (2009)
Mammalian embryo: branching morphogenesis.
Encyclopedia of Life Sciences Article
A741
Davies JA (2009) The
embryonic kidney: isolation, organ culture,immunostaining and RNA interference.
Chapter in
Mouse Cell Culture. Editor
- Ward. A.† (Humana Press, ISBN 978-1588297723)
Unbekandt M & Davies
JA (2009) Control of Organogenesis. Chapter in
Fundamentals of Tissue Engineering and Regenerative
Medicine (Springer).
Sweeney D, Lindstrˆm N,
Davies JA (2008) Developmental plasticity and regenerative capacity† in the
renal ureteric bud/collecting duct system.
Development
135:2505-2510.
PubMed
McMahon AP, Aronow
B, Davidson D, Davies JA, Gaido K, Grimmond S, Lessard J, Little M, Potter S,
Wilder E, Zhang P (2008) GUDMAP – the genito-urinary developmental
molecular anatomy project.†
J. Am Soc
Nephrol 19: 667-671.
PubMed
Davies JA (2008)
Synthetic Morphology: prospects for engineered, self-constructing anatomies.
J. Anat
212:707-19
PubMed
Lee, WC, Berry, R,
Hohenstein, P and Davies, JA (2008) siRNA as a tool for investigating
organogenesis – the pitfalls and the promises.
Organogenesis
4(3):176-81.
PubMed
Davies J (2008)
Cellular
mechanisms of morphogenesis.
Scholarpedia, 3(2):3615
Blenkiron M,
Arvind DK, Davies JA (2007) Design of an irreversible DNA memory element.
Natural Computing 6: 403-411
Davies JA (2007)
Developmental biologists’ choice of subjects approximates to a power law,
with no evidence for the existence of a special group of organisms’.
BMC Dev Biol (2007) 7:40
PubMed
Little M, Brennan J, Georgas K, Davies J, Davidson D, Beverdam A, Bertram, J,
Capel B, Christiansen E, Cullen L, Fleming J, Gilbert T, Herzlinger D, Kaufman
M, Kleymenova E, Koopman P, Kris W, Lewis A, McMahon A, Mendelsohn C, Mitchell
E, Saunders P, Spencer T, Spears N, Sweeney D, Thomson A, Valerius T, Yamada G,
Yu J.(2006). High-resolution anatomical ontologies of the developing murine
genitourinary tract for the annotation of data from the Genitourinary
Development Murine Atlas Project.
MoD Gene Expr Patterns 7 :680-99
PubMed
Davies JA (2007) Epithelial branching: the power of self loathing.
BioEssays
29: 205-7
PubMed
Murray P, Camussi
G, Davies J, Egdar D, Hengstschlaeger M, Kenny M, Remuzzi G, Werner C. (2007)
The KIDSTEM European Research Training Network
Organogenesis 3: 2-4
PubMed
Michael L, Sweeney
D,Davies JA(2007) The lectin, Dolichos biflorus agglutinin, is a sensitive
indicator of branching morphogenetic activity in the developing mouse
metanephric collecting duct system.
J. Anat. 210: 89-97
PubMed
Davies JA (2006) A
method for cold storage and transport of viable kidney rudiments.
Kidney
International 70, 2031–2034.
PubMed
Davies JA
(2006)Branching Morphogenesis of Mammalian epithelia. Chapter in
Principles
of developmental genetics
Davies JA(2006)
The embryonic kidney: isolation, organ culture, immunostaining and RNA
interference. Chapter in
Mouse Cell Culture Eds Ward A and Tosh
D.
Lee WC and Davies
JA (2006). Dapper1 and dapper2 are expressed in distinct parts of developing
metanephroi. Nephrol Dial Transplant. 21(Suppl 4): 18-9
Davies JA (2006)
Renal Structure and Function in Vertebrates (Hans Ditrich), book review.
J. Anat 208, issue 3, start page 391
Davies JA, Armstrong
J (2006) The anatomy of organogenesis: novel solutions to old problems.
Progr. Histochem Cytochem
Willnow TE, Antignac
C, Brandli A, Christensen EI, Cox RD, Davidson D, Davies JA, Devuyst O, Eichele
E, Hastie N, Verroust P, Schedl A, Meij IC(2005) The European Renal Genome
Project – an integrated approach towards understanding the genetics of
kidney development and disease.
Organogenesis PubMed
Michael L, Sweeney DE, Davies JA(2005) A role for microfilament-based contraction in
branching morphogenesis of the ureteric bud.
Kidney
International 68: 2010-2018
PubMed
Davies JA (2005) Watching tubules glow and branch.
Curr Op Genet
Dev 15:364-370
PubMed
Davies JA (2005)Mechanisms of Morphogenesis(Book).
Elsevier
Davies J [Ed.] (2005)
Branching Morphogenesis (Book). Landes/ Springer
Davies JA (2005) Branching
morphogenesis in the mammalian kidney. In Davies JA (Ed)
Branching
Morphogenesis. Landes/ Springer
Davies JA (2004) Inverse
correlation between an organ’s cancer rate and its evolutionary
antiquity."
Organogenesis 1: 60-63
PubMed
Michael L, Davies JA (2004) Pattern and regulation
of cell proliferation during morphogenesis of the mouse ureteric bud.
J. Anat 204: 241-255.
PubMed
Davies JA, Ladomery M,
Hohenstein P, Michael L, Spraggon L, Schafe A, Freeman
T, Hastie N (2004)Development
of an siRNA-based method for repressing specific genes in renal organ culture
and its use to show that the Wt1 tumour suppressor is required for nephron
differentiation.
Hum Mol Genet13: 235-46
PubMed
Davies JA,Yates E, Turnbull J (2003) Importance of 2-O-sulphation for interactions
between heparin and the GDNF signalling system.
Growth Factors 21:109-119
Davies JA (2003) Modulation of developmental signalling by
GAGs.
Recent Research Developments in Biochemistry
283-301
PubMed
Davies JA (2003) Journals: impact factors are too highly valued.
Nature† 421: 210.
PubMed
Barnett MW, Fisher CE, Perona-Wright G, Davies JA (2002) Signalling
by glial cell line-derived neurotrophic factor (GDNF) requires heparan sulphate
glycosaminoglycan.
J Cell Sci 115: 4495-4503
PubMed
Davies JA (2002) Do different branching epithelia use a conserved
developmental mechanism?
BioEssays. 24: 937-948
PubMed
Davies JA (2002) Morphogenesis of the kidney.
TheScientificWorld
Journal 2: 120-
Davies JA (2002) The Kidney Development Database. Chapter in
Analyzing Gene Expression, Ed Stefan Lorkowski
Davies JA (2002) The individual success of musicians, like that of
physicists, follows a stretched exponential distribution.
Eur Physics J
B 27:445-447
This paper was the subject of an article in The Guardian,
18th July 2002
Davies JA & Fisher CE (2002) “Genes in renal
development”
Experimental Nephrology 10: 102-113
PubMed
Davies, JA (2002) The Extracellular Matrix (
Encyc Life Sci,
article 1274).
Davies JA (2002) Development of the collecting duct system –
chapter in
The Development of the Kidney (Eds Bard and
Vize).
Fisher C, Barnett M, Davies JA (2001) Erk MAP-kinase regulates
branching morphogenesis in the developing mouse kidney. Development 128:
4329-4338.
PubMed
Davies JA, Fisher CE, Barnett MW (2001) Glycosaminoglycans in the
study of mammalian organ development.
Biochem. Soc. Trans. 29:
166-171.
Davies JA (2001) Branching Morphogenesis of the Urinary Collecting
Ducts.
Journal of Anatomy 198: 257-264
Davies JA, Perera A, Walker C (1999) Mechanisms of† epithelial
development and neoplasia in the developing kidney.
Int Rev Dev Biol 43:
473-478
PubMed
Davies JA & Davey MD (1999) Collecting duct morphogenesis.
Paediatric† Nephrology 13: 535-541
PubMed
Davies JA (1999) The Kidney Development Database.
Dev Genet
24: 194-198.
PubMed
Davies JA, Millar CB, Johnson E, Milbrandt J (1999) Regulation of
renal† collecting duct development by neurturin.
Dev Genet 24:
284-292
PubMed
Milbrandt J, de Sauvage F, Fahrner TL, Baloh RH, Leitner ML, Tansey
ML, Lampe PA, Heuckeroth RO, Kotzbauer PT, Simburger KS, Golden JP, Davies JA,
Vejsads R, Kato AC, Hynes M, Sherman D, Nishimura M, Wang L-C, Vandlen R,
Moffat B, Klein RD, Poulsen K, Gray C, Garces A, Henderson CE, Phillips HS,
Johnson E (1998) Persephin, a neurotrophic factor related to GDNF and
Neurturin.
Neuron 20:1-20
PubMed
Davies JA and Bard JBL (1998) Development of the metanephric kidney.
Curr. Top. Dev. Biol. 39: 245-302
Davies JA, Hunter DA, Brandli A , Nieminen P (1997) Design
considerations for small, special system developmental databases.
Seminars
in Cell & Dev Biol 8:519-525.
PubMed
Sainio K, Suvanto P, Davies JA, Wartiovaara J, Wartiovaara K, Saarma
M, Arum‰e U, Meng X, Lindahl M, Pachnis V, Sariola H (1997) Glial cell-line
derived neurotrophic factor is required for bud initiation from ureteric
epithelium.
Development 124: 4077-4087
PubMed
Davies JA, Garrod DRG (1997) Molecular aspects of the epithelial
phenotype.
BioEssays19,
699-704
PubMed
Davies JA, Buchman VL, Krylova O, Ninkina NN (1997) Molecular cloning
and expression pattern of rpr-1, a resiniferatoxin-binding,
phosphotriesterase-related protein expressed in rat kidney tubules.
FEBS
Lett 410, 378-382
PubMed
Davies JA (1996) Mesenchyme to epithelium transition during
development of the mammalian kidney tubule.
Acta Anatomica (in
press)
PubMed
Davies JA, Bard JBL (1996) Inductive interactions between the renal
mesenchyme and the ureteric bud.
Experimental Nephrology 4:
77-85
PubMed
Bard JBL, Davies JA, Karavanova I, Lehtonen E, Sariola H, Vainio S
(1996) Kidney development: the inductive interactions.
Sem in Cell & Dev
Biol 7: 195-202.
Bard J.B.L. and Davies JA (1996) Development, Databases and the
Internet.
BioEssays 17999-1001
PubMed
Papers co-written by JAD before he had his own lab:
Davies JA, Lyon M, Gallagher J, Garrod DR (1995) Sulphated
proteoglycan is required for collecting duct growth and branching but not
nephron formation during kidney development.
Development 121
1507-1517
PubMed
Davies JA, Garrod DR (1995) Induction of early stages of kidney tubule
differentiation by lithium ions.
Dev. Biol. 167
50-60
PubMed
Davies JA (1994) Control of Calbindin-D-28K expression in developing mouse kidney. Devel. Dynam. 199 45-51
Davies JA (1993) How to build a kidney. Sem in Cell Biol 4 (1993) 213-219
Davies JA, Cook GMW (1991) Growth cone inhibition - an important mechanism in neural development? BioEssays 13 11-15
Cook GMW, Davies JA, Keynes RJ (1991). Growth cone collapse - a simple assay for monitoring cell-cell repulsion Methodological surveys in biochemistry and analysis, sub-series B : biochemistry 21: 359-366, 1991
Keynes R, Cook G, Davies J, Lumsden A, Norris W, Stern C (1990) Segmentation and the development of the nervous system. J. Physiol (Paris) 84; :27-32
Davies JA, Cook GMW, Stern CD, Keynes RJ (1990) Isolation from chick somites of a glycoprotein fraction that causes collapse of dorsal root ganglion growth cones. Neuron 4 11-20