We are trying to apply what has been learned about normal organ development to the problem of engineering new organs (for drug testing and, one day, for transplantation)
We make as much use as possible of cells' own ability to self-organize. So far, we have managed to produce, from suspensions of separated foetal stem cells, engineered 'foetal kdineys' that consist of a branched uring collecting duct system, with attached nephrons, in a self-organized organ that has a distinct medulla and cortex. These kidneys are capable of connecting to a host blood system. We are currently testing how well they work.